Nutrilite Health Institute Clinical Investigations and Trials

Nutrilite Health Institute clinical investigations and trials are focused on intervention studies to evaluate the effects of plant concentrates, botanicals, and nutrient products on markers of human health. The Nutrilite Health Institute also continues Nutrilite founder Carl Rehnborg's commitment to scientifically-based products through clinical research programs.

A clinical study involves the evaluation of the functions of plant concentrates, and product prototypes in volunteers in a carefully controlled clinical setting and under the supervision of medical health care professionals.

Why do we do clinical research?

  • Research - to advance science and knowledge regarding the benefits of dietary supplements and plant-based ingredients, and their mechanisms of action. We want to know not just if a product works, but also how it works.
  • Reputation - specifically, to maintain Nutrilite's strong reputation for selling science-based supplements. As needed we conduct clinical research to evaluate the performance of Nutrilite ingredients and/or formulas. When we make claims about our products, we have confidence and stand behind them. We do not make claims we cannot substantiate.
  • Integrity - to protect the integrity and trust of the Nutrilite® brand.

To date, we have completed:

  • 60 clinical studies on Nutrilite® concentrates, products, and prototypes - some of this research is never seen by the public because if a prototype does not work, it does not become a Nutrilite® product.
  • 7 large scale nutrition assessment studies.

These numbers represent research conducted over 60 years at 30 external research sites in seven different countries.

Helps increase plasma folate concentrations

Study at a Glance

Goal: Find out how Nutrilite® Vitamin B compares to consumption of folic acid-fortified foods and foods naturally high in folate at increasing plasma folate and how it affects plasma homocysteine levels.

Results: After six weeks, plasma folate concentrations increased while homocysteine levels decreased in the Supplement and Fortified groups, but not in the other groups.

Conclusion: Nutrilite® Vitamin B supplementation may be a convenient and effective way to ensure consistent and high plasma concentrations of folate.

For more information, please refer to the Nutrilite® Vitamin B clinical research summary.

Nutrilite Health Institute clinical trial showed that Double X® supplement boosts blood levels of beneficial nutrients and provides functional benefits to maintain healthy living.

Study at a Glance

Goal: To evaluate the ability of Nutrilite® Double X® supplement to deliver key nutrients often lacking in the typical "Western" diet, as compared to individuals consuming a more "optimal" diet of fruits and vegetables.

Results: Those who took Double X® supplement had higher levels of vitamins B6, B12, and folate in their plasma; reduced homocysteine levels; higher levels of the antioxidant nutrients beta-carotene and vitamin E; and less DNA damage compared to before they took Double X®.

Conclusion: This study demonstrates beneficial nutrients in Double X® supplement are absorbed by the body and that functional benefits - antioxidant protection from cell-damaging free radicals - are detectable in healthy adults, suggesting that Double X® supplement helps support healthy aging.

For more information, please refer to the Nutrilite® Double X® clinical research summary.

Nutrilite Health Institute clinical trial showed that ClearGuard® dietary supplement helps support clear nasal passages.

Study at a Glance

Goal: Surveys conducted in the United States reveal that a significant proportion of the population have utilized botanical products for the treatment of nasal allergy symptoms, although there have been relatively few controlled clinical trials to support their use.

In a pilot randomized double-blind placebo-controlled trial published in Nutrition Journal, July 14, 2008, however, a combination of three botanical ingredients—Spanish needles, cinnamon (Cinnamomum zeylanicum), and acerola (Malpighia glabra)— the three key ingredients found in Nutrilite® ClearGuard® dietary supplement, were studied to determine their effectiveness at clearing nasal passages.

Results: The three key ingredients found in Nutrilite® ClearGuard® dietary supplement were shown to be safe and effective at clearing nasal passages.

Conclusion: Nutrilite® ClearGuard® clearing nasal passages.

For more information, please refer to the Nutrilite® ClearGuard® clinical research summary.

Human gene expression gives insight into how Nutrilite® Immunity Echinacea works.

Study at a Glance

Goal: To utilize gene expression technology to examine Echinacea's effects in humans.

Results: Following two days of supplementation with Nutrilite® Immunity Echinacea, specific immunity gene activity increased while the activity of several "pro-inflammatory" genes decreased.

Conclusion: Supplementation with Nutrilite® Immunity Echinacea had a visible effect on the expression of genes related to immunity.

For more information, please refer to the Nutrilite® Immunity Echinacea clinical research summary.

Research sponsored by Nutrilite Health Institute and conducted by the Urological Sciences Research Foundation using the Saw Palmetto and Nettle Root herbal blend in Nutrilite® Prostate Health was named "The Most Scientifically Exciting" by the American Urological Association.

Study at a Glance

Goal: To evaluate whether the Saw Palmetto with Nettle root herbal blend improves the condition of Benign Prostatic Hyperplasia (BPH), a common problem for aging males.

Results: After Six months of supplementation with the Saw Palmetto with Nettle Root herbal blend, supports men's prostate function. The herbal blend also helps support normal urinary flow.

This was the first US-based double-blind, placebo-controlled clinical trial to evaluate a Saw Palmetto product.

For more information, please refer to the Nutrilite® Prostate Health clinical research summary.

The Nutrilite Health Institute clinical trial showed that the IL-1 Heart Health dietary supplement helps balance IL-1 gene expression in people who test positive for the IL-1 gene.

Study at a Glance

Goal: To test the effect of consuming the recommended daily serving of IL-1 Heart Health.

Results: In those who tested positive for the IL-1 gene, supplementation with IL-1 Heart Health led to a:

·         60% reduction in IL-1 gene expression

·         40% reduction in IL-1 production

·         20% reduction in CRP (C-Reactive Protein)in 45 % of the individuals

Conclusion: This study demonstrates that the Nutrilite® IL-1 Heart Health dietary supplement helps balance gene expression for people who over express IL-1. This supplement also helps maintain normal CRP for those already in the normal range.

For more information, please refer to the IL-1 Heart Health clinical research summary.